Top 10 Best Saigon to Siem Reap Cruise 2025, Love by US Travellers
Heritage Line Jayavarman Cruise Upstream 8 days: Saigon - Siem Reap
9.4Excellent - 53 reviewsEverything was first class and fantastic. Recommend this cruise highly. Loved every…Mr. Peter Moore -Australia
Ho Chi Minh City - Mekong Delta - Cai Be - Sa Dec - Tan Chau - Phnom Penh - Siem ReapSuitable: Couples & Honeymoon, Luxury Travellers, SeniorsHighlights- Enjoy off-the-beaten-path authentic spiritual and cultural heritage along Mekong River rivulets
- Navigate through the legendary Mekong Delta, uncovering the charm of unique waterway culture and local communities
- Indulge in the diverse flavors of Vietnamese and Cambodian culinary tapestry of the region
- Get to know Cambodian history and charming temples in Phnom Penh and Siem Reap
View tour5% offUSD$2,403$2,403/paxHeritage Line Jahan Cruise Upstream 8 days: Saigon - Siem Reap
9.4Excellent - 66 reviewsWe really enjoy our trip. The staff was very nice, especially Vietnamese guide.…Ms. Avra Jain -United States
Ho Chi Minh City - Cai Be - Tan Chau - Phnom Penh - Siem Reap - Mekong DeltaHighlights- Appreciate all the beauty from the enchanting world-famous heritage sites to the pure natural landscape of Vietnam and Cambodia
- Learn about the Mekong Rivulets' history through cultural spots and bustling lifestyle along the way upstream
- Join the locals with off-the-beaten-track experiences
View tour5% offUSD$2,604$2,604/paxRV Mekong Princess Cruise Upstream 8 days: Saigon - Siem Reap
9.6Excellent - 9 reviewsWe had beautiful eight days on Mekong Princess Cruise. The trip was worthwhile and…Mr.Adam Rothenberg -United States
Ho Chi Minh City - Ben Tre - Can Tho - Cu Lao Gieng Island - Phnom Penh - Kampong Cham - Siem…- Holiday Season Sale: 35% OFF!
Theme: Interact with local, NatureSuitable: Couples & HoneymoonHighlights- Immerse in the tranquility and untouched beauty of the Mekong River
- Explore several traditional crafts in Vietnamese villages
- Experience the authentic local life
View tour30% offUSD$2,604$2,120/paxRV Mekong Navigator Cruise Upstream 8 days: Saigon - Siem Reap
Ho Chi Minh City - My Tho - Cai Be - Sa Dec - Phnom Penh - Kampong Cham - Siem ReapTheme: CulturalHighlights- “Mekong Delta” themed dinner introduces the innovation of Southeast Asia cuisine
- Explore the intricate network of canals, discovering the essence of the Mekong Delta's rural life.
- Set sail to Cai Be, where the Mekong's charm reveals itself in the form of a floating market
- Explore the UNESCO World Heritage site Angkor Wat
- Marvel at the architectural splendor of historical spots that stand as a testament to the grandeur of the Khmer Empire
View tourUSD$2,699$2,219/paxVictoria Mekong Cruise Upstream 8 days: Saigon - Siem Reap
9.6Excellent - 4 reviewsWhat can we say. Perfect from beginning to end. The journey from Ho Chi Minh City…Tyson M -Australia
Ho Chi Minh City - Mekong Delta - Tan Chau - Can Tho - Phnom Penh - Kampong Cham - Siem ReapTheme: Off the beaten track, Relaxation, CulturalSuitable: Couples & Honeymoon, Luxury Travellers, SeniorsHighlights- Sail across the Mekong Delta and witness the local life and one-of-a-kind river culture
- Immerse in Vietnamese and Cambodian culture in a totally extraordinary way
- Explore the typical bustling Southwest countryside of Vietnam with handcrafted villages
- Visit most famous historical attractions of Phnom Penh and admire their unique local lives
View tour49% offUSD$1,942$1,942/paxToum Tiou II Cruise Upstream 9 days: Saigon - Siem Reap
9.0Excellent - 13 reviewsHotels were very good. Staff at Hanoi hotel were excellent, best we have encountered…Mr. David Madden -Australia
Ho Chi Minh City - My Tho - Sa Dec - Phnom Penh - Kampong Chhnang - Cai Be - Chau Doc - Kampong…Highlights- Cruise along the mighty Mekong River
- Explore the colorful floating markets and villages
- Discover Phnom Penh and get to know the locals of Kampong Chhnang
- Visit ancient temples and small villages
View tour$1,682Pandaw Mekong Cruise Upstream 8 days: Saigon - Siem Reap
9.3Excellent - 22 reviewsWe thoroughly enjoyed the Pandaw cruise and would recommend others to do it. We…Ms. Annette Plowman -Australia
Mekong Delta - Ho Chi Minh City - My Tho - Ben Tre - Chau Doc - Phnom Penh - Kampong Tralach…Highlights- Pass along the River Mekong, with its fascinating and varied tapestry of river life
- Experience the striking cultural contrast between the bustling Vietnam delta and the tranquility of Cambodia
- Travel through the vast and rich Delta region, witnessing the incredible richness of human life and endeavor
- Explore the vibrant French colonial port of Saigon
- Discover the stunning Cambodian countryside, with its exotic flora and fauna and fascinating cultural traditions
- Spend a full day in charming Phnom Penh
- Explore remoter waterways as you progress to the great monuments of Angkor
Toum Tiou I Cruise Upstream 8 days: Saigon - Siem Reap
9.3Excellent - 13 reviewsFreindly Staff and great food. The Toum Tiou cruise was exellent. We arrived early…Mr. John R Magnay -Australia
Ho Chi Minh City - Can Tho - Cai Be - Vinh Long - Phnom Penh - Siem Reap - Sa Dec - Chau Doc…Highlights- Admire the amazing canal network of Mekong Delta
- Enjoy the senses of the bustling floating markets
- Explore the waterway Saigon – Siem Reap with its people vivid daily life
- Experience the culture and taste the typical foods with special cuisines
View tour26% offUSD$1,644$1,644/paxRV La Marguerite Cruise Upstream 8 days: Saigon - Siem Reap
9.0Excellent - 10 reviewsYour guides where excellent we would happly recommend this houlday to all our friends…Mr. John Henwood -Australia
Ho Chi Minh City - My Tho - Cai Be - Sa Dec - Tan Chau - Phnom Penh - Kampong Cham - Siem…Highlights- Enjoy an exciting city tour of Phnom Penh - the majestic capital of Cambodia retains its French charm.
- Cruise past the Mekong’s timeless villages with extensive fishing activities.
- Explore the pre-Angkorian temple located on top of a hill overlooking the Mekong.
- Discovery and experience of various wonderful handcrafting villages
View tour$1,756RV Mekong Prestige II Cruise Upstream 8 days: Saigon - Siem Reap
9.4Excellent - 32 reviewsCruise was 10/10 in all aspects. Staff excellentMs.Deneses Smith -Australia
Ho Chi Minh City - My Tho - Sa Dec - Cai Be - Tan Chau - Phnom Penh - Chong Koh Village -…Theme: CulturalHighlights- Admire the pristine sceneries and immerse in the peacefulness of Tonle Sap Lake
- Explore the history of the former capital of Cambodia - Angkor
- Join in the bustling life of Saigon to find the city's hidden charm and local culture
View tourUSD$2,300$2,300/pax
FAQs
U.S citizens will need a valid visa for a Saigon to Siem Reap cruise.
Vietnam Visa
We strongly recommend applying for a Vietnam e-Visa in advance, preferably through a reputable agency such as BestPrice Travel (US$ 40/person).
NOTE: Make sure your passport is valid for at least 6 months beyond your entry date.
Cambodia Visa
For the upstream cruise to Siem Reap, your cruise line will assist with visa-on-arrival processing at the water border.
- Cost: US$50 - $75/person.
- Required: Passport (valid for at least 6 months), 1 passport-size photo, cash for the visa fee.
A Saigon to Siem Reap cruise typically costs between US$ 1,514 and $4,316 per person for an 8-day itinerary. It can vary depending on the cruise line, cabin type, and season.
Here are some of the most recommended Saigon-Siem Reap river cruises for US tourists with great reviews and the best rates (price excludes transfer fee).
- RV Mekong Princess - From US$ 2,120/pax: Elegant French-colonial design.
- Heritage Line Jayavarman - From US$ 2,403/pax: An aesthetic floating art gallery.
- RV La Marguerite - From US$ 1,702/pax: Refined design and opulent facilities.
- Heritage Line Jahan - From US$ 2,604/pax: Premium services and resort-like amenities.
- RV Mekong Navigator - From US$ 2,402/pax: Luxurious lounge, bar, and La Vie spa.
After disembarking in Siem Reap, here are the top activities you can enjoy for 2 - 4 day stays:
- Explore Angkor Wat & nearby Temples (Bayon Temple, Ta Prohm,...).
- Visit Tonlé Sap Lake: boat tour to floating villages like Kampong Phluk or Khleang.
- Enjoy Culture & Nightlife: visit Phare Circus, stroll Pub Street, or shop at Night Markets for souvenirs.
- Try a Khmer Cooking Class: Learn to make amok, spring rolls, or curry,...
- Relax: Affordable massages or spa treatments, visit a cafè or rooftop bar to unwind.
Most Mekong River cruises between Saigon and Siem Reap last 8 days and 7 nights, providing ample time to explore the Mekong Delta, Phnom Penh, and surrounding areas. Some itineraries may vary slightly depending on the water level.