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Most Mekong River cruises between Saigon and Siem Reap last 8 days and 7 nights, providing ample time to explore the Mekong Delta, Phnom Penh, and surrounding areas. Some itineraries may vary slightly depending on the water level.

U.S citizens will need a valid visa for a Saigon to Siem Reap cruise.

Vietnam Visa

We strongly recommend applying for a Vietnam e-Visa in advance, preferably through a reputable agency such as BestPrice Travel (US$ 40/person).

NOTE: Make sure your passport is valid for at least 6 months beyond your entry date. 

Cambodia Visa 

For the upstream cruise to Siem Reap, your cruise line will assist with visa-on-arrival processing at the water border.

  • Cost: US$50 - $75/person.
  • Required: Passport (valid for at least 6 months), 1 passport-size photo, cash for the visa fee.

Here are some of the most recommended Saigon-Siem Reap river cruises for US tourists with great reviews and the best rates (price excludes transfer fee).

  • RV Mekong Princess - From US$ 2,120/pax: Elegant French-colonial design.
  • Heritage Line Jayavarman - From US$ 2,403/pax: An aesthetic floating art gallery.
  • RV La Marguerite - From US$ 1,702/pax: Refined design and opulent facilities.
  • Heritage Line Jahan - From US$ 2,604/pax: Premium services and resort-like amenities.
  • RV Mekong Navigator - From US$ 2,402/pax: Luxurious lounge, bar, and La Vie spa.

A Saigon to Siem Reap cruise typically costs between US$ 1,514 and $4,316 per person for an 8-day itinerary. It can vary depending on the cruise line, cabin type, and season.

After disembarking in Siem Reap, here are the top activities you can enjoy for 2 - 4 day stays:

  • Explore Angkor Wat & nearby Temples (Bayon Temple, Ta Prohm,...).
  • Visit Tonlé Sap Lake: boat tour to floating villages like Kampong Phluk or Khleang.
  • Enjoy Culture & Nightlife: visit Phare Circus, stroll Pub Street, or shop at Night Markets for souvenirs.
  • Try a Khmer Cooking Class: Learn to make amok, spring rolls, or curry,...
  • Relax: Affordable massages or spa treatments, visit a cafè or rooftop bar to unwind.
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